New lipid nanoparticle design improves precision of mRNA vaccine delivery

Penn Engineers have redesigned a key component of lipid nanoparticles (LNPs), the delivery vehicles behind mRNA vaccines, to ...
News-Medical.Net

Modified lipid nanoparticles boost mRNA vaccines while reducing side effects

The most common side effects of mRNA vaccines like the COVID-19 shot are well known: soreness, mild fever and general malaise ...
Medical Xpress

Modified mRNA vaccine masquerades as a virus to trick the body into stronger immunity

A more effective vaccine technology may be on the horizon. In a new study in mice, researchers from the University of Copenhagen demonstrate that a simple addition to mRNA vaccines can significantly ...
BioWorld

Study finds link between NAT10-mediated ac4C modification and seizure behavior in epileptic mice

N4-Acetylation of cytidine (ac4C) is an mRNA modification that enhances cellular mRNA stability and translation. Most eukaryotic organisms catalyze ac4C using a homologue of human N-acetyltransferase ...