The space between the arachnoid and pia meningeal layers encasing the brain is a landscape of connective tissue, blood vessels, and cerebrospinal fluid. Scientists debate how that fluid moves within ...

The typical signs and symptoms of idiopathic NPH are shown. In a retrospective study involving 418 patients with shunt-responsive idiopathic NPH, 96% of the patients had gait difficulty, 76% had ...

Approximately 400,000 cases of infantile and childhood hydrocephalus occur worldwide annually. 1 For most affected patients, treatment is inadequate because of limited access to care. Left untreated, ...

Research headed by teams at the University of Rochester Center for Translational Medicine and the University of Copenhagen describes for the first time how a spreading wave of disruption and the flow ...

Chiari malformation type I (CMI) is a congenital neurological disorder characterized by the herniation of cerebellar tonsils through the foramen magnum, leading to impaired cerebrospinal fluid (CSF) ...

A major international study has uncovered a new biological clue that could help predict dementia long before memory problems arise. Researchers from the University of Cambridge and Zhejiang University ...

Using single-cell sequencing, researchers found distinct immune profiles in different CNS tumors, highlighting its potential as a prognostic tool.

A novel blood and cerebrospinal fluid (CSF) measure showed promise as a biomarker for Parkinsonian disorders. CSF levels of DOPA decarboxylase (DDC) -- an enzyme that converts levodopa into dopamine - ...

With age, the brain’s ability to clear aggregating proteins such as Aβ wanes. In the November 9 Nature, researchers led by Jonathan Kipnis at Washington University in St. Louis suggest a reason why.